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Safer CRISPR gene editing with fewer off-target hits

The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeutic potential, but runs the risk of inappropriately editing ”off-target” sites. However, a new study shows that mutating the enzyme at the heart of the CRISPR gene editing system can improve its fidelity.

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Safer CRISPR gene editing with fewer off-target hits

The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeutic potential, but runs the risk of inappropriately editing ”off-target” sites. However, a new study shows that mutating the enzyme at the heart of the CRISPR gene editing system can improve its fidelity.

A new look at deep-sea microbes

(University of Delaware) Microbes found deeper in the ocean are believed to have slow population turnover rates and low amounts of available energy. But a new examination of microbial communities found deeper in seafloor sediments and around hydrocarbon seepage sites has found they have more energy available and a higher population turnover. The deeper sediments in the seepages are most likely heavily impacted by the material coming up from the bottom, which means that the seep could be supporting a larger amount of biomass than previously thought.

Lead fallout from Notre Dame fire was likely overlooked

(Earth Institute at Columbia University) A new study, published today in GeoHealth, used soil samples collected from neighborhoods around the cathedral to estimate local amounts of lead fallout from the fire.

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UCLA receives Department of Energy grant to transform CO2 into construction materials

(University of California – Los Angeles) A UCLA research team has received a two-year, $2 million grant from the US Department of Energy to support development of a process that can convert carbon dioxide emissions into construction materials. The technology they devised captures carbon dioxide from raw flue gas as it exits power plants, cement plants and other producers of carbon dioxide, reducing emissions to the atmosphere. The process also cuts down on the use of traditional cement.

To Defeat The Climate Cult, Realists Need To Unite, Speak Out

Much is made of the fact that former “climate change” advocates have now defected to the side of reason. But much more needs to be done to defeat climate change propaganda. The latest defection, as we’ve noted here, is Michael…

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Norman Conquest of 1066 did little to change people’s eating habits

Archaeologists have combined the latest scientific methods to offer new insights into life during the Norman Conquest of England. Until now, the story of the Conquest has primarily been told from evidence of the elite classes of the time. But little has been known about how it affected everyday people’s lives.

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Norman Conquest of 1066 did little to change people’s eating habits

Archaeologists have combined the latest scientific methods to offer new insights into life during the Norman Conquest of England. Until now, the story of the Conquest has primarily been told from evidence of the elite classes of the time. But little has been known about how it affected everyday people’s lives.